BDBM24433 (3R,5R)-7-[3,4-bis(4-fluorophenyl)-1-methyl-5-(phenylcarbamoyl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoic acid::Pyrrole Series 5 Compound, 20

SMILES: Cn1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)c(c(c1C(=O)Nc1ccccc1)-c1ccc(F)cc1)-c1ccc(F)cc1

InChI Key: InChIKey=FCFBTCOXDIMJOM-JWQCQUIFSA-N

Data: 1 ITC

PDB links: 2 PDB IDs contain this monomer as substructures. 2 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 24433

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) (Homo sapiens (Human))	BDBM24433 ((3R,5R)-7-[3,4-bis(4-fluorophenyl)-1-methyl-5-(phe...)	GoogleScholar PDB	KEGG PC cid PC sid		-10.9	0.500	-11.4	7.84	7.20	30
Pfizer Inc.					J Med Chem 51: 3804-13 (2008)