null
SMILES: CC[C@@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2[nH]c(nc2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@H](C)CC
InChI Key: InChIKey=QTYPOCIPHFOPOW-AVALWUNLSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein [1657-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM245926![]() (US9433609, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.00300 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist... | US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1973-2419,Y2165H] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM245926![]() (US9433609, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 5.19 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr... | US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1657-3011] (Hepatitis C virus genotype 1a (isolate H77) (HCV)) | BDBM245926![]() (US9433609, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.471 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr... | US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [1657-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM245926![]() (US9433609, 19) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a |
Janssen Sciences Ireland UC US Patent | Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr... | US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD | |||||||||||
More data for this Ligand-Target Pair |