Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1657-3011]' and Ligand = 'BDBM245926'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein [1657-3011] (Hepatitis C virus genotype 1a (isolate H77) (HCV))	BDBM245926 (US9433609, 19) Show SMILES CC[C@@H](C)[C@H](NC(=O)OC)C(=O)N1CCC[C@H]1c1ncc([nH]1)-c1ccc2cc(ccc2c1)-c1ccc2[nH]c(nc2c1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)[C@H](C)CC |r| Show InChI InChI=1S/C44H52N8O6/c1-7-25(3)37(49-43(55)57-5)41(53)51-19-9-11-35(51)39-45-24-34(48-39)31-16-15-27-21-28(13-14-29(27)22-31)30-17-18-32-33(23-30)47-40(46-32)36-12-10-20-52(36)42(54)38(26(4)8-2)50-44(56)58-6/h13-18,21-26,35-38H,7-12,19-20H2,1-6H3,(H,49,55)(H,50,56)/b30-28+,34-31-/t25-,26-,35+,36+,37+,38+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.471	n/a	n/a	n/a	n/a
Janssen Sciences Ireland UC US Patent					Assay Description In a transient set-up, a Huh-7 lunet hepatoma cell line was transiently transfected with an autonomously replicating RNA encoding a bi-cistronic expr...				US Patent US9433609 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60FD
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