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SMILES: COc1ccccc1-n1nc(OC2CN(C2)C(=O)OC(C)(C)C)cc1-c1ccc(Cl)cc1

InChI Key: InChIKey=AZSLSVQTOKQPLV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246328   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-dependent L-type calcium channel subunit beta-3/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1


(Homo sapiens (Human))		BDBM246328
PNG
(US9434693, 22)
Show SMILES COc1ccccc1-n1nc(OC2CN(C2)C(=O)OC(C)(C)C)cc1-c1ccc(Cl)cc1
Show InChI InChI=1S/C24H26ClN3O4/c1-24(2,3)32-23(29)27-14-18(15-27)31-22-13-20(16-9-11-17(25)12-10-16)28(26-22)19-7-5-6-8-21(19)30-4/h5-13,18H,14-15H2,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 67n/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...

US Patent US9434693 (2016)


BindingDB Entry DOI: 10.7270/Q29S1PZJ
More data for this
Ligand-Target Pair