BDBM246333 US9434693, 28

SMILES: CC(C)Oc1ccccc1-n1nc(OC2CCN(CC2)S(=O)(=O)C(C)C)cc1-c1ccc(Cl)cc1

InChI Key: InChIKey=RIAAESBLPRZGAK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-type calcium channel subunits alpha 1B (Cav2.2), Beta 3, and Alpha 2 Delta (Homo sapiens (Human))	BDBM246333 (US9434693, 28) Show SMILES CC(C)Oc1ccccc1-n1nc(OC2CCN(CC2)S(=O)(=O)C(C)C)cc1-c1ccc(Cl)cc1 Show InChI InChI=1S/C26H32ClN3O4S/c1-18(2)33-25-8-6-5-7-23(25)30-24(20-9-11-21(27)12-10-20)17-26(28-30)34-22-13-15-29(16-14-22)35(31,32)19(3)4/h5-12,17-19,22H,13-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description Calcium mobilization responses to KCl depolarization were evaluated by measuring the intensity of calcium-mediated fluorescent signal in the presence...				US Patent US9434693 (2016) BindingDB Entry DOI: 10.7270/Q29S1PZJ
					More data for this Ligand-Target Pair