null
SMILES: N=C(NCCN1CCOCC1)c1nc2ccc3ncnc(Nc4ccc5OCOc5c4)c3c2s1
InChI Key: InChIKey=RQOMVYKSFXEJAW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human)) | BDBM246359 (US9446044, 29) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
DIAXONHIT US Patent | Assay Description The DYRK1A and DYRK1B kinase assays to determine IC50 values were performed by Reaction Biology Corporation using HotSpot technology Worldwide websit... | US Patent US9446044 (2016) BindingDB Entry DOI: 10.7270/Q2610Z7J | |||||||||||
More data for this Ligand-Target Pair |