null

SMILES: Cn1c2oc(c(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O)-c1cccc(Cl)c1

InChI Key: InChIKey=ZYKNKRIATZOUNQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM246466 (US9447114, 27) Show SMILES Cn1c2oc(c(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C23H20Cl2N2O4/c1-26-22-19(21(29)27(23(26)30)10-3-11-28)18(12-14-6-8-16(24)9-7-14)20(31-22)15-4-2-5-17(25)13-15/h2,4-9,13,28H,3,10-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	7.2	n/a
Hydra Biosciences, Inc. US Patent					Assay Description TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...				US Patent US9447114 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NRD
					More data for this Ligand-Target Pair
Short transient receptor potential channel 5 (Homo sapiens (Human))	BDBM246466 (US9447114, 27) Show SMILES Cn1c2oc(c(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O)-c1cccc(Cl)c1 Show InChI InChI=1S/C23H20Cl2N2O4/c1-26-22-19(21(29)27(23(26)30)10-3-11-28)18(12-14-6-8-16(24)9-7-14)20(31-22)15-4-2-5-17(25)13-15/h2,4-9,13,28H,3,10-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	134	n/a	n/a	n/a	n/a	7.4	25
Hydra Biosciences, Inc. US Patent					Assay Description The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...				US Patent US9447114 (2016) BindingDB Entry DOI: 10.7270/Q2ST7NRD
					More data for this Ligand-Target Pair