BDBM246470 4-(4-Methoxyphenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine (5b)

SMILES: COc1ccc(cc1)-c1cc(nc(N)n1)-c1ccc2n(C)c3ccccc3c2c1

InChI Key: InChIKey=LQEHHFTZKROWFV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246470   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM246470 (4-(4-Methoxyphenyl)-6-(9-methyl-9H-carbazol-3-yl)-...) Show SMILES COc1ccc(cc1)-c1cc(nc(N)n1)-c1ccc2n(C)c3ccccc3c2c1 Show InChI InChI=1S/C24H20N4O/c1-28-22-6-4-3-5-18(22)19-13-16(9-12-23(19)28)21-14-20(26-24(25)27-21)15-7-10-17(29-2)11-8-15/h3-14H,1-2H3,(H2,25,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.54E+4	n/a	n/a	n/a	n/a	6.8	30
Solapur University					Assay Description Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...				J Enzyme Inhib Med Chem 28: 1316-23 (2013) Article DOI: 10.3109/14756366.2012.740477 BindingDB Entry DOI: 10.7270/Q2J965BH
					More data for this Ligand-Target Pair