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BDBM246472 4-(9-Methyl-9H-carbazol-3-yl)-6-(2,4,6-trimethoxyphenyl)-pyrimidin-2-amine (5d)

SMILES: COc1cc(OC)c(c(OC)c1)-c1cc(nc(N)n1)-c1ccc2n(C)c3ccccc3c2c1

InChI Key: InChIKey=LIPMYNSREYDLKH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246472   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urease


(Canavalia ensiformis (Jack bean) (Horse bean))		BDBM246472
PNG
(4-(9-Methyl-9H-carbazol-3-yl)-6-(2,4,6-trimethoxyp...)
Show SMILES COc1cc(OC)c(c(OC)c1)-c1cc(nc(N)n1)-c1ccc2n(C)c3ccccc3c2c1
Show InChI InChI=1S/C26H24N4O3/c1-30-21-8-6-5-7-17(21)18-11-15(9-10-22(18)30)19-14-20(29-26(27)28-19)25-23(32-3)12-16(31-2)13-24(25)33-4/h5-14H,1-4H3,(H2,27,28,29)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.37E+4n/an/an/an/a6.830



Solapur University



Assay Description
Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...

J Enzyme Inhib Med Chem 28: 1316-23 (2013)


Article DOI: 10.3109/14756366.2012.740477
BindingDB Entry DOI: 10.7270/Q2J965BH
More data for this
Ligand-Target Pair