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BDBM246475 4-(3,4-Difluorophenyl)-6-(9-methyl-9H-carbazol-3-yl)-pyrimidin-2-amine (5g)

SMILES: Cn1c2ccccc2c2cc(ccc12)-c1cc(nc(N)n1)-c1ccc(F)c(F)c1

InChI Key: InChIKey=UMTUKKJZAJFTRH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246475   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urease


(Canavalia ensiformis (Jack bean) (Horse bean))		BDBM246475
PNG
(4-(3,4-Difluorophenyl)-6-(9-methyl-9H-carbazol-3-y...)
Show SMILES Cn1c2ccccc2c2cc(ccc12)-c1cc(nc(N)n1)-c1ccc(F)c(F)c1
Show InChI InChI=1S/C23H16F2N4/c1-29-21-5-3-2-4-15(21)16-10-13(7-9-22(16)29)19-12-20(28-23(26)27-19)14-6-8-17(24)18(25)11-14/h2-12H,1H3,(H2,26,27,28)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.52E+4n/an/an/an/a6.830



Solapur University



Assay Description
Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...

J Enzyme Inhib Med Chem 28: 1316-23 (2013)


Article DOI: 10.3109/14756366.2012.740477
BindingDB Entry DOI: 10.7270/Q2J965BH
More data for this
Ligand-Target Pair