BDBM246481 4-(9-Methyl-9H-carbazol-3-yl)-6-(4-nitrophenyl)-pyrimidin-2-amine (5m)

SMILES: Cn1c2ccccc2c2cc(ccc12)-c1cc(nc(N)n1)-c1ccc(cc1)[N+]([O-])=O

InChI Key: InChIKey=XCJKLKICHPVYFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246481   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM246481 (4-(9-Methyl-9H-carbazol-3-yl)-6-(4-nitrophenyl)-py...) Show SMILES Cn1c2ccccc2c2cc(ccc12)-c1cc(nc(N)n1)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H17N5O2/c1-27-21-5-3-2-4-17(21)18-12-15(8-11-22(18)27)20-13-19(25-23(24)26-20)14-6-9-16(10-7-14)28(29)30/h2-13H,1H3,(H2,24,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.72E+4	n/a	n/a	n/a	n/a	6.8	30
Solapur University					Assay Description Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...				J Enzyme Inhib Med Chem 28: 1316-23 (2013) Article DOI: 10.3109/14756366.2012.740477 BindingDB Entry DOI: 10.7270/Q2J965BH
					More data for this Ligand-Target Pair