BindingDB logo
myBDB logout

BDBM246482 4-(9-Methyl-9H-carbazol-3-yl)-6-(thiophen-2-yl)-pyrimidin-2-amine (5n)

SMILES: Cn1c2ccccc2c2cc(ccc12)-c1cc(nc(N)n1)-c1cccs1

InChI Key: InChIKey=RJRHTGXBEVDSJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246482   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urease


(Canavalia ensiformis (Jack bean) (Horse bean))		BDBM246482
PNG
(4-(9-Methyl-9H-carbazol-3-yl)-6-(thiophen-2-yl)-py...)
Show SMILES Cn1c2ccccc2c2cc(ccc12)-c1cc(nc(N)n1)-c1cccs1
Show InChI InChI=1S/C21H16N4S/c1-25-18-6-3-2-5-14(18)15-11-13(8-9-19(15)25)16-12-17(24-21(22)23-16)20-7-4-10-26-20/h2-12H,1H3,(H2,22,23,24)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/a6.830



Solapur University



Assay Description
Mixture of 25 μL of urease enzyme (Jack bean) solution containing 1 unit of enzyme (1 unit = 0.02 mg of enzyme) was dissolved in phosphate buffe...

J Enzyme Inhib Med Chem 28: 1316-23 (2013)


Article DOI: 10.3109/14756366.2012.740477
BindingDB Entry DOI: 10.7270/Q2J965BH
More data for this
Ligand-Target Pair