BDBM246812 Cis-11-(benzyloxy)-10-methoxy-3,3-dimethyl-7-oxo-1,2,3,3a,7,12b-hexahydrocyclopenta[c]pyrido[2,1-a]isoquinoline-6-carboxylic acid::US10053461, 3::US10053461, 4

SMILES: COc1cc-2c(cc1OCc1ccccc1)[C@H]1CCC(C)(C)[C@H]1n1cc(C(O)=O)c(=O)cc-21

InChI Key: InChIKey=BYYGXRULNNHJTL-NSYGIPOTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Large envelope protein (Hepatitis B virus)	BDBM246812 (Cis-11-(benzyloxy)-10-methoxy-3,3-dimethyl-7-oxo-1...) Show SMILES COc1cc-2c(cc1OCc1ccccc1)[C@H]1CCC(C)(C)[C@H]1n1cc(C(O)=O)c(=O)cc-21 |r| Show InChI InChI=1S/C27H27NO5/c1-27(2)10-9-17-18-11-24(33-15-16-7-5-4-6-8-16)23(32-3)12-19(18)21-13-22(29)20(26(30)31)14-28(21)25(17)27/h4-8,11-14,17,25H,9-10,15H2,1-3H3,(H,30,31)/t17-,25+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10053461 (2018) BindingDB Entry DOI: 10.7270/Q2Q81G3D
					More data for this Ligand-Target Pair
Large envelope protein (Hepatitis B virus)	BDBM246812 (Cis-11-(benzyloxy)-10-methoxy-3,3-dimethyl-7-oxo-1...) Show SMILES COc1cc-2c(cc1OCc1ccccc1)[C@H]1CCC(C)(C)[C@H]1n1cc(C(O)=O)c(=O)cc-21 |r| Show InChI InChI=1S/C27H27NO5/c1-27(2)10-9-17-18-11-24(33-15-16-7-5-4-6-8-16)23(32-3)12-19(18)21-13-22(29)20(26(30)31)14-28(21)25(17)27/h4-8,11-14,17,25H,9-10,15H2,1-3H3,(H,30,31)/t17-,25+/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	25
Hoffmann-La Roche Inc. US Patent					Assay Description HepG2.2.15 cells were seeded in duplicate into white, 96-well plates at 1.5×104 cells/well. The cells were treated with a three-fold serial dilution ...				US Patent US10053461 (2018) BindingDB Entry DOI: 10.7270/Q2Q81G3D
					More data for this Ligand-Target Pair