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SMILES: C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1

InChI Key: InChIKey=INTRMZVYAODVMS-UDWUOZNQSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247465   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))		BDBM247465
PNG
(US9453023, 24)
Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 |r|
Show InChI InChI=1S/C22H27FN2O2S/c1-16-3-2-14-25(16)21-11-6-18(15-21)17-4-9-20(10-5-17)24-28(26,27)22-12-7-19(23)8-13-22/h4-5,7-10,12-13,16,18,21,24H,2-3,6,11,14-15H2,1H3/t16-,18-,21?/m0/s1
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
 12.4n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...

US Patent US9453023 (2016)


BindingDB Entry DOI: 10.7270/Q2XD10MK
More data for this
Ligand-Target Pair