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SMILES: C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccccc2OC(F)(F)F)cc1

InChI Key: InChIKey=WUVPDSIVRZJNIG-WWKKGYIRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 247476   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine receptor H3


(Macaca mulatta (Rhesus macaque))		BDBM247476
PNG
(US9453023, 35)
Show SMILES C[C@H]1CCCN1C1CC[C@@H](C1)c1ccc(NC(=O)c2ccccc2OC(F)(F)F)cc1 |r|
Show InChI InChI=1S/C24H27F3N2O2/c1-16-5-4-14-29(16)20-13-10-18(15-20)17-8-11-19(12-9-17)28-23(30)21-6-2-3-7-22(21)31-24(25,26)27/h2-3,6-9,11-12,16,18,20H,4-5,10,13-15H2,1H3,(H,28,30)/t16-,18-,20?/m0/s1
UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
US Patent
 136n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
Rhesus H3 radioligand binding assay was performed using rhesus H3 receptor membranes (prepared as described above), [3H]-Methylhistamine (Perkin Elme...

US Patent US9453023 (2016)


BindingDB Entry DOI: 10.7270/Q2XD10MK
More data for this
Ligand-Target Pair