BDBM248055 5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one (6f)

SMILES: O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)C2=CCCC2)CC1

InChI Key: InChIKey=CTRJCSXYHYSJGC-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 248055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM248055 (5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazi...) Show SMILES O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)C2=CCCC2)CC1 |t:24| Show InChI InChI=1S/C22H25N5O/c28-22-24-20-6-5-19(12-21(20)25-22)27-9-7-26(8-10-27)15-16-11-18(14-23-13-16)17-3-1-2-4-17/h3,5-6,11-14H,1-2,4,7-10,15H2,(H2,24,25,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70	-12.4	n/a	n/a	n/a	n/a	n/a	7.4	37
King Fahd University of Petroleum & Minerals					Assay Description Human-cloned 5-HT1A serotonin receptors stably expressed in HEK293-EBNA cells (Perkin-Elmer, Waltham, MA) were radiolabeled with 1.0nM [3H]-8-OH-DPAT...				J Enzyme Inhib Med Chem 29: 281-91 (2014) Article DOI: 10.3109/14756366.2013.776556 BindingDB Entry DOI: 10.7270/Q2SN07WV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM248055 (5-(4-((5-cyclopentenylpyridin-3-yl)methyl)piperazi...) Show SMILES O=c1[nH]c2ccc(cc2[nH]1)N1CCN(Cc2cncc(c2)C2=CCCC2)CC1 |t:24| Show InChI InChI=1S/C22H25N5O/c28-22-24-20-6-5-19(12-21(20)25-22)27-9-7-26(8-10-27)15-16-11-18(14-23-13-16)17-3-1-2-4-17/h3,5-6,11-14H,1-2,4,7-10,15H2,(H2,24,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.10	-11.6	n/a	n/a	n/a	n/a	n/a	7.4	25
King Fahd University of Petroleum & Minerals					Assay Description Human-cloned dopamine D2L receptors stably expressed in C6 rat glioma cells (kindly donated by Professor Roberto Maggio, Università di L'Aquil...				J Enzyme Inhib Med Chem 29: 281-91 (2014) Article DOI: 10.3109/14756366.2013.776556 BindingDB Entry DOI: 10.7270/Q2SN07WV
					More data for this Ligand-Target Pair