BDBM248415 US9434711, 279

SMILES: OC(=O)c1ccc(cc1)S(=O)(=O)N(CC1CCCCC1)c1sc2ccccc2c1Br

InChI Key: InChIKey=GGKWMWWPRRNMLE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248415   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (TRPM8) (Canis lupus familiaris (Dog))	BDBM248415 (US9434711, 279) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(CC1CCCCC1)c1sc2ccccc2c1Br Show InChI InChI=1S/C22H22BrNO4S2/c23-20-18-8-4-5-9-19(18)29-21(20)24(14-15-6-2-1-3-7-15)30(27,28)17-12-10-16(11-13-17)22(25)26/h4-5,8-13,15H,1-3,6-7,14H2,(H,25,26)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
					More data for this Ligand-Target Pair