BDBM248602 US9434711, 521
SMILES: Cc1c(sc2ccccc12)N(Cc1ccc(Cl)c(F)c1)S(=O)(=O)c1ccc(cc1)C(O)=O
InChI Key: InChIKey=YNLGQWBFJIBXJO-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential M8 protein (TRPM8) (Canis lupus familiaris (Dog)) | BDBM248602 (US9434711, 521) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | 37 |
Janssen Pharmaceutica, N.V. US Patent | Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi... | US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6 | |||||||||||
More data for this Ligand-Target Pair |