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SMILES: CS(=O)(=O)Nc1c(Cl)cc(cc1Cl)S(=O)(=O)N(CCC(F)(F)F)c1sc2ccccc2c1Cl

InChI Key: InChIKey=PMFJCYACAKFRNB-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248730   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential M8 protein


(Canis lupus familiaris (Dog))		BDBM248730
PNG
(US9434711, 681)
Show SMILES CS(=O)(=O)Nc1c(Cl)cc(cc1Cl)S(=O)(=O)N(CCC(F)(F)F)c1sc2ccccc2c1Cl
Show InChI InChI=1S/C18H14Cl3F3N2O4S3/c1-32(27,28)25-16-12(19)8-10(9-13(16)20)33(29,30)26(7-6-18(22,23)24)17-15(21)11-4-2-3-5-14(11)31-17/h2-5,8-9,25H,6-7H2,1H3
PDB

KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 67.4n/an/an/an/an/a37



Janssen Pharmaceutica, N.V.

US Patent


Assay Description
The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...

US Patent US9434711 (2016)


BindingDB Entry DOI: 10.7270/Q2H41QB6
More data for this
Ligand-Target Pair