BDBM248758 US9434711, 711

SMILES: OC(=O)c1ccc(c(F)c1)S(=O)(=O)N(Cc1ccc(F)c(c1)C(F)(F)F)c1sc2ccccc2c1Br

InChI Key: InChIKey=NXXAFZWJTVVENR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248758   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential M8 protein (TRPM8) (Canis lupus familiaris (Dog))	BDBM248758 (US9434711, 711) Show SMILES OC(=O)c1ccc(c(F)c1)S(=O)(=O)N(Cc1ccc(F)c(c1)C(F)(F)F)c1sc2ccccc2c1Br Show InChI InChI=1S/C23H13BrF5NO4S2/c24-20-14-3-1-2-4-18(14)35-21(20)30(11-12-5-7-16(25)15(9-12)23(27,28)29)36(33,34)19-8-6-13(22(31)32)10-17(19)26/h1-10H,11H2,(H,31,32)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica, N.V. US Patent					Assay Description The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...				US Patent US9434711 (2016) BindingDB Entry DOI: 10.7270/Q2H41QB6
					More data for this Ligand-Target Pair