BDBM249362 US9464062, 6

SMILES: CC(C)(C)N1CC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)OC1=O

InChI Key: InChIKey=JASFTBXZDINFFH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM249362 (US9464062, 6) Show SMILES CC(C)(C)N1CC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)OC1=O Show InChI InChI=1S/C25H33N3O2/c1-25(2,3)28-19-22(30-24(28)29)18-26-14-16-27(17-15-26)23(20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-13,22-23H,14-19H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.87E+3	n/a	n/a	n/a	n/a	7.4	n/a
TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION US Patent					Assay Description A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...				US Patent US9464062 (2016) BindingDB Entry DOI: 10.7270/Q2Z60MZC
					More data for this Ligand-Target Pair