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SMILES: O=C1OC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)CN1C1CC1

InChI Key: InChIKey=NXSJZUVQWSGQBQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 249363   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM249363
PNG
(US9464062, 7)
Show SMILES O=C1OC(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)CN1C1CC1
Show InChI InChI=1S/C24H29N3O2/c28-24-27(21-11-12-21)18-22(29-24)17-25-13-15-26(16-14-25)23(19-7-3-1-4-8-19)20-9-5-2-6-10-20/h1-10,21-23H,11-18H2
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US Patent
n/an/a 298n/an/an/an/a7.4n/a



TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

US Patent


Assay Description
A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...

US Patent US9464062 (2016)


BindingDB Entry DOI: 10.7270/Q2Z60MZC
More data for this
Ligand-Target Pair