BDBM25000 4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine::oxadiazole-containing compound, 11c

SMILES: CCn1c(nc2c(ncc(OCCCN)c12)-c1cc[nH]c1)-c1nonc1N

InChI Key: InChIKey=BFFORFSCMCLHMJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM25000 (4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1cc[nH]c1)-c1nonc1N Show InChI InChI=1S/C17H20N8O2/c1-2-25-15-11(26-7-3-5-18)9-21-12(10-4-6-20-8-10)13(15)22-17(25)14-16(19)24-27-23-14/h4,6,8-9,20H,2-3,5,7,18H2,1H3,(H2,19,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM25000 (4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1...) Show SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1cc[nH]c1)-c1nonc1N Show InChI InChI=1S/C17H20N8O2/c1-2-25-15-11(26-7-3-5-18)9-21-12(10-4-6-20-8-10)13(15)22-17(25)14-16(19)24-27-23-14/h4,6,8-9,20H,2-3,5,7,18H2,1H3,(H2,19,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	7.5	22
GlaxoSmithKline					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...				J Med Chem 51: 5663-79 (2008) Article DOI: 10.1021/jm8004527 BindingDB Entry DOI: 10.7270/Q29G5K3H
					More data for this Ligand-Target Pair