BDBM250324 US10501411, Example 234::US9452980, 234

SMILES: FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1

InChI Key: InChIKey=UJRCBGVSNLVYNW-OAHLLOKOSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 250324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (TAAR1) (Rattus norvegicus (Rat))	BDBM250324 (US10501411, Example 234 | US9452980, 234) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H19F3N2O/c20-19(21,22)16-5-1-3-14(11-16)18(25)24-17-8-6-13(7-9-17)15-4-2-10-23-12-15/h1,3,5-9,11,15,23H,2,4,10,12H2,(H,24,25)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	-12.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, hea...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Rattus norvegicus (Rat))	BDBM250324 (US10501411, Example 234 | US9452980, 234) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H19F3N2O/c20-19(21,22)16-5-1-3-14(11-16)18(25)24-17-8-6-13(7-9-17)15-4-2-10-23-12-15/h1,3,5-9,11,15,23H,2,4,10,12H2,(H,24,25)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Rat: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentr...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM250324 (US10501411, Example 234 | US9452980, 234) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H19F3N2O/c20-19(21,22)16-5-1-3-14(11-16)18(25)24-17-8-6-13(7-9-17)15-4-2-10-23-12-15/h1,3,5-9,11,15,23H,2,4,10,12H2,(H,24,25)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	21.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (TAAR1) (Mus musculus (Mouse))	BDBM250324 (US10501411, Example 234 | US9452980, 234) Show SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(cc1)[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C19H19F3N2O/c20-19(21,22)16-5-1-3-14(11-16)18(25)24-17-8-6-13(7-9-17)15-4-2-10-23-12-15/h1,3,5-9,11,15,23H,2,4,10,12H2,(H,24,25)/t15-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	21.7	-10.9	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair