BDBM250590 US10167273, Example 69::US10544126, Example 69::US9475795, 69

SMILES: Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1

InChI Key: InChIKey=YFBCBQGTAZLNKK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250590 (US10167273, Example 69 | US10544126, Example 69 | ...) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C18H23Cl2N3O3S/c1-12-17(13(2)22(3)21-12)27(25,26)23-8-6-18(24,7-9-23)11-14-4-5-15(19)16(20)10-14/h4-5,10,24H,6-9,11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.47E+3	n/a	n/a	n/a	n/a	7.4	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US9475795 (2016) BindingDB Entry DOI: 10.7270/Q20Z727W
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250590 (US10167273, Example 69 | US10544126, Example 69 | ...) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C18H23Cl2N3O3S/c1-12-17(13(2)22(3)21-12)27(25,26)23-8-6-18(24,7-9-23)11-14-4-5-15(19)16(20)10-14/h4-5,10,24H,6-9,11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US10544126 (2020) BindingDB Entry DOI: 10.7270/Q2MP55NK
					More data for this Ligand-Target Pair
Prokineticin receptor 1 (Homo sapiens (Human))	BDBM250590 (US10167273, Example 69 | US10544126, Example 69 | ...) Show SMILES Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(O)(Cc2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C18H23Cl2N3O3S/c1-12-17(13(2)22(3)21-12)27(25,26)23-8-6-18(24,7-9-23)11-14-4-5-15(19)16(20)10-14/h4-5,10,24H,6-9,11H2,1-3H3	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat...				US Patent US10167273 (2019) BindingDB Entry DOI: 10.7270/Q24F1ST0
					More data for this Ligand-Target Pair