BDBM250632 US10167273, Example 111::US10544126, Example 111::US9475795, 111
SMILES: Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(CC1)C(C(F)F)c1ccc(Cl)cc1
InChI Key:
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prokineticin receptor 1 (Homo sapiens (Human)) | BDBM250632 (US10167273, Example 111 | US10544126, Example 111 ...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Takeda Pharmaceutical Company Limited US Patent | Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat... | US Patent US9475795 (2016) BindingDB Entry DOI: 10.7270/Q20Z727W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prokineticin receptor 1 (Homo sapiens (Human)) | BDBM250632 (US10167273, Example 111 | US10544126, Example 111 ...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent | Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat... | US Patent US10544126 (2020) BindingDB Entry DOI: 10.7270/Q2MP55NK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prokineticin receptor 1 (Homo sapiens (Human)) | BDBM250632 (US10167273, Example 111 | US10544126, Example 111 ...) | MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Takeda Pharmaceutical Company Limited US Patent | Assay Description Prokineticin receptor 1 (PKR1) antagonists may be functionally assessed by measurement of change in intracellular calcium levels induced by Gq mediat... | US Patent US10167273 (2019) BindingDB Entry DOI: 10.7270/Q24F1ST0 | |||||||||||
More data for this Ligand-Target Pair |