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BDBM251409 US9452990, 91

SMILES: COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(C)C)c1ccc(F)c(c1)C#N

InChI Key: InChIKey=AJYBJOXNPYCEOC-GNLPSFAGNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 251409   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CVF-Bb Complex


(Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)
BDBM251409
PNG
(US9452990, 91)
Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(CC1)C(=O)C[C@@H](NC(C)C)c1ccc(F)c(c1)C#N
Show InChI InChI=1/C27H31F2N7O3/c1-15(2)32-20(16-5-6-19(28)17(11-16)14-30)13-22(37)35-7-9-36(10-8-35)27-33-24-18(26(31)34-27)12-21(38-3)25(39-4)23(24)29/h5-6,11-12,15,20,32H,7-10,13H2,1-4H3,(H2,31,33,34)/t20-/s2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/an/an/a



NOVARTIS AG

US Patent


Assay Description
CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...


Citation and Details
More data for this
Ligand-Target Pair