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SMILES: C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(F)c(OCC2CCC2)c1)-c1cc(C)nc(C)c1

InChI Key: InChIKey=ICBVQPHEUDNHQW-GOSISDBHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 252701   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))		BDBM252701
PNG
(US9458176, 98)
Show SMILES C[C@@H]1Cn2c(CCO1)c(nc2-c1ccc(F)c(OCC2CCC2)c1)-c1cc(C)nc(C)c1 |r|
Show InChI InChI=1S/C26H30FN3O2/c1-16-11-21(12-17(2)28-16)25-23-9-10-31-18(3)14-30(23)26(29-25)20-7-8-22(27)24(13-20)32-15-19-5-4-6-19/h7-8,11-13,18-19H,4-6,9-10,14-15H2,1-3H3/t18-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.10n/an/an/an/an/a25



Eisai R&D Management Co., Ltd.

US Patent


Assay Description
The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...

US Patent US9458176 (2016)


BindingDB Entry DOI: 10.7270/Q2PK0F3D
More data for this
Ligand-Target Pair