BDBM25322 2-bromo-3,5-dinitro-N-[(phenylcarbamoyl)amino]benzamide::ChemBridge N-phenylhydrazinecarboxamide, 17
SMILES: [O-][N+](=O)c1cc(C(=O)NNC(=O)Nc2ccccc2)c(Br)c(c1)[N+]([O-])=O
InChI Key: InChIKey=GSLFCLBARLUAMP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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ATP phosphoribosyltransferase (Mycobacterium tuberculosis) | BDBM25322 (2-bromo-3,5-dinitro-N-[(phenylcarbamoyl)amino]benz...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | 8.5 | 22 |
Yale University | Assay Description Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ... | J Med Chem 51: 5984-92 (2008) Article DOI: 10.1021/jm800328v BindingDB Entry DOI: 10.7270/Q2V986CX | |||||||||||
More data for this Ligand-Target Pair |