BDBM25339 N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-{2-[2-(morpholin-4-yl)-2-oxoacetamido]propan-2-yl}-6-oxo-1,6-dihydropyrimidine-4-carboxamide::N-methyl-pyrimidinone derivative, 15

SMILES: Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C(C)(C)NC(=O)C(=O)N1CCOCC1

InChI Key: InChIKey=DWNWXQVKMRJASU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM25339 (N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-{2...) Show SMILES Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C(C)(C)NC(=O)C(=O)N1CCOCC1 Show InChI InChI=1S/C22H26FN5O6/c1-22(2,26-18(31)20(33)28-8-10-34-11-9-28)21-25-15(16(29)19(32)27(21)3)17(30)24-12-13-4-6-14(23)7-5-13/h4-7,29H,8-12H2,1-3H3,(H,24,30)(H,26,31)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.8	37
Merck Research Laboratories					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 51: 5843-55 (2008) Article DOI: 10.1021/jm800245z BindingDB Entry DOI: 10.7270/Q2QJ7FMR
					More data for this Ligand-Target Pair