BDBM25435 4-[(1S,2S)-2-hydroxycyclohexyl]-2-(trifluoromethyl)benzonitrile::arylcyclohexanol, (+)-6a

SMILES: O[C@H]1CCCC[C@H]1c1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=MENRRRXHFQYXDW-AAEUAGOBSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM25435 (4-[(1S,2S)-2-hydroxycyclohexyl]-2-(trifluoromethyl...) Show SMILES O[C@H]1CCCC[C@H]1c1ccc(C#N)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C14H14F3NO/c15-14(16,17)12-7-9(5-6-10(12)8-18)11-3-1-2-4-13(11)19/h5-7,11,13,19H,1-4H2/t11-,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	7.4	4
Pfizer					Assay Description The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...				J Med Chem 51: 7010-4 (2008) Article DOI: 10.1021/jm8009316 BindingDB Entry DOI: 10.7270/Q2Z31WZ1
					More data for this Ligand-Target Pair