BDBM254857 US9493412, 85

SMILES: CN1CC(C(=O)NCc2cccc(c2)-c2ccc(CNC(C)=O)cc2)=C(O)C1=O

InChI Key: InChIKey=XQNOQQSTRWQFMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM254857 (US9493412, 85) Show SMILES CN1CC(C(=O)NCc2cccc(c2)-c2ccc(CNC(C)=O)cc2)=C(O)C1=O |t:26| Show InChI InChI=1S/C22H23N3O4/c1-14(26)23-11-15-6-8-17(9-7-15)18-5-3-4-16(10-18)12-24-21(28)19-13-25(2)22(29)20(19)27/h3-10,27H,11-13H2,1-2H3,(H,23,26)(H,24,28)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	241	n/a	n/a	n/a	n/a	8.0	n/a
Bristol-Myers Squibb Company US Patent					Assay Description Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...				US Patent US9493412 (2016) BindingDB Entry DOI: 10.7270/Q2FX78CV
					More data for this Ligand-Target Pair