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SMILES: CCN1CC(C(=O)N[C@@H]2CCC(c3ccccc3)c3ccccc23)=C(O)C1=O

InChI Key: InChIKey=CYZIZTQBLIJVAS-OTOKDRCRSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254863   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM254863
PNG
(US9493412, 146)
Show SMILES CCN1CC(C(=O)N[C@@H]2CCC(c3ccccc3)c3ccccc23)=C(O)C1=O |r,t:26|
Show InChI InChI=1S/C23H24N2O3/c1-2-25-14-19(21(26)23(25)28)22(27)24-20-13-12-16(15-8-4-3-5-9-15)17-10-6-7-11-18(17)20/h3-11,16,20,26H,2,12-14H2,1H3,(H,24,27)/t16?,20-/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 50.0n/an/an/an/a8.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...

US Patent US9493412 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78CV
More data for this
Ligand-Target Pair