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SMILES: CN1CC(C(=O)NCC2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)=C(O)C1=O

InChI Key: InChIKey=XHFYDOOANISKRL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254864   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelial lipase


(Homo sapiens (Human))		BDBM254864
PNG
(US9493412, 157)
Show SMILES CN1CC(C(=O)NCC2CCN(CC2)C(=O)c2ccc(Cl)c(Cl)c2)=C(O)C1=O |t:25|
Show InChI InChI=1S/C19H21Cl2N3O4/c1-23-10-13(16(25)19(23)28)17(26)22-9-11-4-6-24(7-5-11)18(27)12-2-3-14(20)15(21)8-12/h2-3,8,11,25H,4-7,9-10H2,1H3,(H,22,26)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.84E+3n/an/an/an/a8.0n/a



Bristol-Myers Squibb Company

US Patent


Assay Description
Endothelial lipase activity was measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artificial vesicle containing DMPG (Av...

US Patent US9493412 (2016)


BindingDB Entry DOI: 10.7270/Q2FX78CV
More data for this
Ligand-Target Pair