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BDBM254879 US9493472, 2

SMILES: COc1cc(cc2nc(N[C@H](CF)c3cccc(Cl)c3)oc12)C(=O)N1CCC(O)C(C)C1

InChI Key: InChIKey=JUKYMUDXJNGELI-HRJVKACCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254879   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM254879
PNG
(US9493472, 2)
Show SMILES COc1cc(cc2nc(N[C@H](CF)c3cccc(Cl)c3)oc12)C(=O)N1CCC(O)C(C)C1 |r|
Show InChI InChI=1S/C23H25ClFN3O4/c1-13-12-28(7-6-19(13)29)22(30)15-9-17-21(20(10-15)31-2)32-23(26-17)27-18(11-25)14-4-3-5-16(24)8-14/h3-5,8-10,13,18-19,29H,6-7,11-12H2,1-2H3,(H,26,27)/t13?,18-,19?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 31n/an/an/an/a7.422



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s...

US Patent US9493472 (2016)


BindingDB Entry DOI: 10.7270/Q2B56HPW
More data for this
Ligand-Target Pair