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BDBM254882 US9493472, 5

SMILES: COc1cc(cc2nc(N[C@H](CF)c3cccc(Cl)c3)oc12)C(=O)N1CC(C)(C)OCC1CO

InChI Key: InChIKey=UZFYJBNAWVIPQP-WHCXFUJUSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254882   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM254882
PNG
(US9493472, 5)
Show SMILES COc1cc(cc2nc(N[C@H](CF)c3cccc(Cl)c3)oc12)C(=O)N1CC(C)(C)OCC1CO |r|
Show InChI InChI=1S/C24H27ClFN3O5/c1-24(2)13-29(17(11-30)12-33-24)22(31)15-8-18-21(20(9-15)32-3)34-23(27-18)28-19(10-26)14-5-4-6-16(25)7-14/h4-9,17,19,30H,10-13H2,1-3H3,(H,27,28)/t17?,19-/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10n/an/an/an/a7.422



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s...

US Patent US9493472 (2016)


BindingDB Entry DOI: 10.7270/Q2B56HPW
More data for this
Ligand-Target Pair