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SMILES: COc1cc(cc2nc(NC(CF)c3cccc(Cl)c3)oc12)C(=O)N1CC2CCN2C(=O)C1C

InChI Key: InChIKey=QDPUMLWGBPJVGR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254901   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prothrombin


(Homo sapiens (Human))		BDBM254901
PNG
(US9493472, 23)
Show SMILES COc1cc(cc2nc(NC(CF)c3cccc(Cl)c3)oc12)C(=O)N1CC2CCN2C(=O)C1C
Show InChI InChI=1S/C24H24ClFN4O4/c1-13-22(31)29-7-6-17(29)12-30(13)23(32)15-9-18-21(20(10-15)33-2)34-24(27-18)28-19(11-26)14-4-3-5-16(25)8-14/h3-5,8-10,13,17,19H,6-7,11-12H2,1-2H3,(H,27,28)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.70n/an/an/an/a7.422



Bayer Pharma Aktiengesellschaft

US Patent


Assay Description
To determine the thrombin inhibition of the substances listed above, a biochemical test system is constructed in which the conversion of a thrombin s...

US Patent US9493472 (2016)


BindingDB Entry DOI: 10.7270/Q2B56HPW
More data for this
Ligand-Target Pair