null
SMILES: CN(C)C(=O)C[C@@H]1N=C(c2ccc(Cl)cc2)c2cc(ccc2-c2c(C)noc12)-c1cnn(C)c1
InChI Key: InChIKey=RXXOWAAYINDZRV-QFIPXVFZSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 [42-168] (Homo sapiens (Human)) | BDBM254914 (US9493483, 402) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | 7.0 | 25 |
Constellation Pharmaceuticals, Inc. US Patent | Assay Description His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed and purified to homogeneity. BRD4 binding and inhibition was assessed by monitoring the ... | US Patent US9493483 (2016) BindingDB Entry DOI: 10.7270/Q26D5RXQ | |||||||||||
More data for this Ligand-Target Pair |