BDBM254970 US9505765, 194

SMILES: NC(=O)\C=C\c1c[nH]c2ncnc(OCc3cccc(F)c3)c12

InChI Key: InChIKey=KFTLSWHJVMUFGV-SNAWJCMRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 7 interacting protein 1 (Homo sapiens (Human))	BDBM254970 (US9505765, 194) Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(OCc3cccc(F)c3)c12 Show InChI InChI=1S/C16H13FN4O2/c17-12-3-1-2-10(6-12)8-23-16-14-11(4-5-13(18)22)7-19-15(14)20-9-21-16/h1-7,9H,8H2,(H2,18,22)(H,19,20,21)/b5-4+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
CONFLUENCE LIFE SCIENCES INC. US Patent					Assay Description TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...				US Patent US9505765 (2016) BindingDB Entry DOI: 10.7270/Q2T43S1J
					More data for this Ligand-Target Pair