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SMILES: NC(=O)\C=C\c1c[nH]c2ncnc(OC3CCC(F)(F)CC3)c12

InChI Key: InChIKey=IIBQLYSZHMEQIH-OWOJBTEDSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254975   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1


(Homo sapiens (Human))		BDBM254975
PNG
(US9505765, 199)
Show SMILES NC(=O)\C=C\c1c[nH]c2ncnc(OC3CCC(F)(F)CC3)c12
Show InChI InChI=1S/C15H16F2N4O2/c16-15(17)5-3-10(4-6-15)23-14-12-9(1-2-11(18)22)7-19-13(12)20-8-21-14/h1-2,7-8,10H,3-6H2,(H2,18,22)(H,19,20,21)/b2-1+
PDB

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US Patent
n/an/a 16n/an/an/an/an/an/a



CONFLUENCE LIFE SCIENCES INC.

US Patent


Assay Description
TAK1-TAB1 Binding Inhibitory Potency: The ability of candidate compounds to interact with TAK1-TAB1 is quantitated by a competitive binding assay usi...

US Patent US9505765 (2016)


BindingDB Entry DOI: 10.7270/Q2T43S1J
More data for this
Ligand-Target Pair