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SMILES: COc1cc(nc(OC)n1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1

InChI Key: InChIKey=DKOOBWVAIQNXPS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM255082 (US9475817, 39) Show SMILES COc1cc(nc(OC)n1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN8O3/c1-31-11-15(21(30-31)13-4-6-14(24)7-5-13)16-8-9-19-26-18(12-32(19)29-16)27-22(33)17-10-20(34-2)28-23(25-17)35-3/h4-12H,1-3H3,(H,27,33)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.2	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu...				US Patent US9475817 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZXH
					More data for this Ligand-Target Pair
Casein kinase I isoform epsilon (Homo sapiens (Human))	BDBM255082 (US9475817, 39) Show SMILES COc1cc(nc(OC)n1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN8O3/c1-31-11-15(21(30-31)13-4-6-14(24)7-5-13)16-8-9-19-26-18(12-32(19)29-16)27-22(33)17-10-20(34-2)28-23(25-17)35-3/h4-12H,1-3H3,(H,27,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	75.7	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu...				US Patent US9475817 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZXH
					More data for this Ligand-Target Pair