null
SMILES: Cn1nc(c(c1N1CCN(CCC(F)(F)F)CC1)-c1ccc2nc(NC(=O)c3ccnc(c3)N3CCOCC3)cn2n1)-c1ccc(F)cc1
InChI Key: InChIKey=QZZVBEDCATULNC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM255176 (US9475817, 135) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... | US Patent US9475817 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZXH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform epsilon (Homo sapiens (Human)) | BDBM255176 (US9475817, 135) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 35 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company US Patent | Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... | US Patent US9475817 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZXH | |||||||||||
More data for this Ligand-Target Pair |