BDBM255621 US9475815, 6

SMILES: COc1cc(C)cc2cc(sc12)-c1cc(CN[C@@H]2CCNC2=O)n2ncnc(N)c12

InChI Key: InChIKey=KZRHBBOXPRPJRS-OAHLLOKOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GST-Fibroblast growth factor receptor 1 (FGFR-1) (Homo sapiens (Human))	BDBM255621 (US9475815, 6) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@@H]2CCNC2=O)n2ncnc(N)c12 |r| Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-17(30-19(12)16(6-11)29-2)14-8-13(9-24-15-3-4-23-21(15)28)27-18(14)20(22)25-10-26-27/h5-8,10,15,24H,3-4,9H2,1-2H3,(H,23,28)(H2,22,25,26)/t15-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.1	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair
GST-Fibroblast growth factor receptor 3 (FGFR-3) (Homo sapiens (Human))	BDBM255621 (US9475815, 6) Show SMILES COc1cc(C)cc2cc(sc12)-c1cc(CN[C@@H]2CCNC2=O)n2ncnc(N)c12 |r| Show InChI InChI=1S/C21H22N6O2S/c1-11-5-12-7-17(30-19(12)16(6-11)29-2)14-8-13(9-24-15-3-4-23-21(15)28)27-18(14)20(22)25-10-26-27/h5-8,10,15,24H,3-4,9H2,1-2H3,(H,23,28)(H2,22,25,26)/t15-/m1/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.7	n/a	n/a	n/a	n/a	7.0	22
BAYER INTELLETUAL PROPERTY GMBH US Patent					Assay Description A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...				US Patent US9475815 (2016) BindingDB Entry DOI: 10.7270/Q2862FC7
					More data for this Ligand-Target Pair