BDBM256029 US9481672, 207
SMILES: CN1C(=O)C(C)(C)c2ccc(cc12)-n1cc(C(O)=O)c(=O)n(Cc2cccc(Cl)c2C(F)(F)F)c1=O
InChI Key: InChIKey=IHCYJSSHGGOLDG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chymase (Mesocricetus auratus (Golden hamster)) | BDBM256029 (US9481672, 207) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description The enzyme source used is recombinant human chymase (expressed in HEK293 cells) or chymase purified from hamsters' tongues. The substrate used for ch... | US Patent US9481672 (2016) BindingDB Entry DOI: 10.7270/Q20P0XZ7 | |||||||||||
More data for this Ligand-Target Pair |