BDBM258756 US9499482, 155

SMILES: COC1CN(CCOc2ccc(cc2OC)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1

InChI Key: InChIKey=VEQHVRMDPRCUAI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 258756   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (MCHR1)(E4Q)(A5T) (Homo sapiens (Human))	BDBM258756 (US9499482, 155) Show SMILES COC1CN(CCOc2ccc(cc2OC)N2CC=C(Oc3ccc(cc3)C3CC3)C2=O)C1 |t:19| Show InChI InChI=1S/C26H30N2O5/c1-30-22-16-27(17-22)13-14-32-23-10-7-20(15-25(23)31-2)28-12-11-24(26(28)29)33-21-8-5-19(6-9-21)18-3-4-18/h5-11,15,18,22H,3-4,12-14,16-17H2,1-2H3	GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description An in vitro binding assay was used to determine the compound Ki value or ability to antagonize binding of a peptide agonist to the human melanin conc...				US Patent US9499482 (2016) BindingDB Entry DOI: 10.7270/Q2M907KT
					More data for this Ligand-Target Pair