Found 4 hits for monomerid = 259462 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
(Homo sapiens (Human)) | BDBM259462
(US9512114, 27)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C28H25N9O2/c1-16(33-26-24(25(29)30-15-31-26)27-35-34-17(2)39-27)22-12-18-8-7-11-21(19-13-32-36(3)14-19)23(18)28(38)37(22)20-9-5-4-6-10-20/h4-16H,1-3H3,(H3,29,30,31,33)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p110α/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol 4,5-bisphosphate and MgATP (concentration as ... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
(Homo sapiens (Human)) | BDBM259462
(US9512114, 27)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C28H25N9O2/c1-16(33-26-24(25(29)30-15-31-26)27-35-34-17(2)39-27)22-12-18-8-7-11-21(19-13-32-36(3)14-19)23(18)28(38)37(22)20-9-5-4-6-10-20/h4-16H,1-3H3,(H3,29,30,31,33)/t16-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p120γ) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as required)... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform
(Homo sapiens (Human)) | BDBM259462
(US9512114, 27)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C28H25N9O2/c1-16(33-26-24(25(29)30-15-31-26)27-35-34-17(2)39-27)22-12-18-8-7-11-21(19-13-32-36(3)14-19)23(18)28(38)37(22)20-9-5-4-6-10-20/h4-16H,1-3H3,(H3,29,30,31,33)/t16-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform
(Homo sapiens (Human)) | BDBM259462
(US9512114, 27)Show SMILES C[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2cccc(-c3cnn(C)c3)c2c(=O)n1-c1ccccc1 |r| Show InChI InChI=1S/C28H25N9O2/c1-16(33-26-24(25(29)30-15-31-26)27-35-34-17(2)39-27)22-12-18-8-7-11-21(19-13-32-36(3)14-19)23(18)28(38)37(22)20-9-5-4-6-10-20/h4-16H,1-3H3,(H3,29,30,31,33)/t16-/m0/s1 | PDB
UniProtKB/SwissProt
UniProtKB/TrEMBL
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | 25 |
CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.
US Patent
| Assay Description
PI3K (p1103/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as requ... |
US Patent US9512114 (2016)
BindingDB Entry DOI: 10.7270/Q2TT4PWS |
More data for this
Ligand-Target Pair | |
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