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SMILES: CNC(=O)C(=C\c1cccc(c1)C(=O)c1c[nH]c2ncccc12)\C#N

InChI Key: InChIKey=KEDKBMWYWUXRQQ-NTEUORMPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259834   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3 [399-740]


(Homo sapiens (Human))		BDBM259834
PNG
(US9505766, 38)
Show SMILES CNC(=O)C(=C\c1cccc(c1)C(=O)c1c[nH]c2ncccc12)\C#N
Show InChI InChI=1S/C19H14N4O2/c1-21-19(25)14(10-20)9-12-4-2-5-13(8-12)17(24)16-11-23-18-15(16)6-3-7-22-18/h2-9,11H,1H3,(H,21,25)(H,22,23)/b14-9+
UniProtKB/SwissProt

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 386n/an/an/an/a8.022



THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

US Patent


Assay Description
RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...

US Patent US9505766 (2016)


BindingDB Entry DOI: 10.7270/Q2639NPR
More data for this
Ligand-Target Pair