null

SMILES: CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cnn(Cc3ccc(F)cc3Cl)c2n1

InChI Key: InChIKey=WKKWCYSKPGGNJJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 259970   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM259970 (US9512132, 6) Show SMILES CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cnn(Cc3ccc(F)cc3Cl)c2n1 Show InChI InChI=1S/C20H21ClF3N5/c1-19(2,3)18-26-16(28-7-6-20(23,24)11-28)14-9-25-29(17(14)27-18)10-12-4-5-13(22)8-15(12)21/h4-5,8-9H,6-7,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.90	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM259970 (US9512132, 6) Show SMILES CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cnn(Cc3ccc(F)cc3Cl)c2n1 Show InChI InChI=1S/C20H21ClF3N5/c1-19(2,3)18-26-16(28-7-6-20(23,24)11-28)14-9-25-29(17(14)27-18)10-12-4-5-13(22)8-15(12)21/h4-5,8-9H,6-7,10-11H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM259970 (US9512132, 6) Show SMILES CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cnn(Cc3ccc(F)cc3Cl)c2n1 Show InChI InChI=1S/C20H21ClF3N5/c1-19(2,3)18-26-16(28-7-6-20(23,24)11-28)14-9-25-29(17(14)27-18)10-12-4-5-13(22)8-15(12)21/h4-5,8-9H,6-7,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.90	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM259970 (US9512132, 6) Show SMILES CC(C)(C)c1nc(N2CCC(F)(F)C2)c2cnn(Cc3ccc(F)cc3Cl)c2n1 Show InChI InChI=1S/C20H21ClF3N5/c1-19(2,3)18-26-16(28-7-6-20(23,24)11-28)14-9-25-29(17(14)27-18)10-12-4-5-13(22)8-15(12)21/h4-5,8-9H,6-7,10-11H2,1-3H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair