BDBM259973 US9512132, 9

SMILES: Cc1nonc1Cn1ncc2c(nc(nc12)C(C)(C)C)N1CCC(F)(F)C1

InChI Key: InChIKey=YLOBYAWMYVSJMP-UHFFFAOYSA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 259973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM259973 (US9512132, 9) Show SMILES Cc1nonc1Cn1ncc2c(nc(nc12)C(C)(C)C)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H21F2N7O/c1-10-12(24-27-23-10)8-26-14-11(7-20-26)13(21-15(22-14)16(2,3)4)25-6-5-17(18,19)9-25/h7H,5-6,8-9H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM259973 (US9512132, 9) Show SMILES Cc1nonc1Cn1ncc2c(nc(nc12)C(C)(C)C)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H21F2N7O/c1-10-12(24-27-23-10)8-26-14-11(7-20-26)13(21-15(22-14)16(2,3)4)25-6-5-17(18,19)9-25/h7H,5-6,8-9H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM259973 (US9512132, 9) Show SMILES Cc1nonc1Cn1ncc2c(nc(nc12)C(C)(C)C)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H21F2N7O/c1-10-12(24-27-23-10)8-26-14-11(7-20-26)13(21-15(22-14)16(2,3)4)25-6-5-17(18,19)9-25/h7H,5-6,8-9H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM259973 (US9512132, 9) Show SMILES Cc1nonc1Cn1ncc2c(nc(nc12)C(C)(C)C)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H21F2N7O/c1-10-12(24-27-23-10)8-26-14-11(7-20-26)13(21-15(22-14)16(2,3)4)25-6-5-17(18,19)9-25/h7H,5-6,8-9H2,1-4H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair