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SMILES: Cc1nonc1Cn1ncc2c(nc(cc12)C1CC1)N1CCC(F)(F)C1

InChI Key: InChIKey=LLNLRGARHFDLBH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 259991   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM259991 (US9512132, 27) Show SMILES Cc1nonc1Cn1ncc2c(nc(cc12)C1CC1)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H18F2N6O/c1-10-14(23-26-22-10)8-25-15-6-13(11-2-3-11)21-16(12(15)7-20-25)24-5-4-17(18,19)9-24/h6-7,11H,2-5,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42.5	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM259991 (US9512132, 27) Show SMILES Cc1nonc1Cn1ncc2c(nc(cc12)C1CC1)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H18F2N6O/c1-10-14(23-26-22-10)8-25-15-6-13(11-2-3-11)21-16(12(15)7-20-25)24-5-4-17(18,19)9-24/h6-7,11H,2-5,8-9H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM259991 (US9512132, 27) Show SMILES Cc1nonc1Cn1ncc2c(nc(cc12)C1CC1)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H18F2N6O/c1-10-14(23-26-22-10)8-25-15-6-13(11-2-3-11)21-16(12(15)7-20-25)24-5-4-17(18,19)9-24/h6-7,11H,2-5,8-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50,000 cells per well in a black 96 well plate with fl...				US Patent US9694012 (2017) BindingDB Entry DOI: 10.7270/Q2VX0DPM
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM259991 (US9512132, 27) Show SMILES Cc1nonc1Cn1ncc2c(nc(cc12)C1CC1)N1CCC(F)(F)C1 Show InChI InChI=1S/C17H18F2N6O/c1-10-14(23-26-22-10)8-25-15-6-13(11-2-3-11)21-16(12(15)7-20-25)24-5-4-17(18,19)9-24/h6-7,11H,2-5,8-9H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
Hoffmann-La Roche Inc. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9512132 (2016) BindingDB Entry DOI: 10.7270/Q2P26X39
					More data for this Ligand-Target Pair